Research

His Most Famous Research

Identical Twins & Aging

Antell is considered a pioneer for studying how lifestyle affects aging by comparing identical twins (who share the same genetics). Key idea: He tried to isolate environment vs. genetics.

What he found was lifestyle factors like sun exposure, smoking, stress, diet, and alcohol can significantly change how a person ages—even compared to their genetically identical twin.

In simple terms, two people with the same DNA can look dramatically different depending on how they live. This work became widely recognized and was even featured in a Smithsonian human genome exhibit, which is unusual for a plastic surgeon .

Serene woman with short gray hair in sunlight wearing gray t-shirt with eyes closed in peaceful contemplation - in New York, NY

Twin-Based Surgical Research

Facelifts

Antell also used twins to study plastic surgery outcomes, which is rare and scientifically valuable.

Example:

  • Compared full-incision vs. short-scar facelifts

Found:

  • Both look similar at first
  • But after ~5 years, short-scar facelifts showed more aging relapse
  • Because twins are genetically identical, this type of study is unusually strong evidence in cosmetic surgery research.

Deep Plane Facelift

Technique & Research

In more recent discussions, Antell talks about advanced facelift methods like the deep plane facelift. His stance is there is no single “best” facelift. The best approach depends on the individual.

He often describes his work as a “designer facelift” tailored to anatomy. He has studied different surgical depths (like SMAS vs deep plane), long-term outcomes, technique comparisons using twin models.

Why His Research Stands Out

  • He has operated on more identical twins than almost any surgeon
  • Twin studies reduce variables → stronger conclusions
  • Bridges:
    • Cosmetic surgery
    • Genetics
    • Lifestyle medicine

Reality Check

While his research is influential in plastic surgery:

  • It’s niche (focused on aesthetics and aging)
  • Some findings (like lifestyle effects) are widely accepted beyond his work
  • His surgical conclusions are respected but still part of an evolving field
Dr Antell consulting with patient walking together in modern medical office hallway - in New York, NY

Bottom Line

“Darrick Antell deep research” usually refers to:

  • Twin studies showing lifestyle > genetics in visible aging
  • Clinical comparisons of facelift techniques
  • Work on customized surgical approaches

From Dr. Antell

At this point in my career, I have performed more facelifts than anyone in the world, on identical twins. Twins who want to remain looking similar, seek me out as if two different surgeons operated on them,… they would get different results.

Attached are two separate landmark papers that were published separately in the Journal of Plastic & Reconstructive Surgery, the most prestigious journal and these articles are frequently referenced by other articles on facelifts. No one else, with the same surgeon operating, has ever done comparison studies like this.

In addition to my publications, I am one of very few plastic surgeons who have BOTH a Dental as well as a Medical degree which provides me a unique appreciation of facial anatomy and aging.

The third paper attached is the original career making article visually proving the effects of Excess Sun, Smoking and Stress (the 3 S’s’) on the aging process. I think you will agree the photos are impressive where one was a nudist (excess sun) or where one smoked for 30 years and her twin sister never did !!!

Save these clean copies as these papers should be featured on the new website and all of this makes me Unique.

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    It is rare to find a physician who combines exceptional surgical talent with genuine kindness and integrity, but Dr. Antel does exactly that. I recommend him with complete confidence to anyone

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    I am extremely grateful for the care I have received over the years and would not hesitate to recommend Dr. Antell and his wonderful team—Rosa, Nancy, and Tiffany—to anyone.

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  • “I’m so pleased and grateful”

    I recently underwent a breast augmentation procedure with Dr. Antell at his New York City office. I’m so pleased and grateful for a seamless experience and successful result.

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  • “Had a fantastic experience”

    Had a fantastic experience with Dr. Antell and his entire team in NYC, Manhattan. From start to finish, they made what could have been a stressful process feel smooth, comfortable, and well-managed.

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  • “Highly recommend”

    Him and his team has always made me feel comfortable through any process/procedure(shoutout to Nancy and Rosa!). Highly recommend.

    Eric L.

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